MB SNiP Screen

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MB SNiP Screen

  • ■  No needles, no fuss!
  • ■  A focus on clinical validity
  • ■  We can screen your DNA for over
    160 traits and conditions including
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  • Related Articles

    Listed below are links to news, reports, and discussion articles related to the science of DNA gene screening.

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    Genetics of diabetes reveals biology but does not improve prediction
    PHG Foundation , 19-Jan-2010

    ABSTRACT: On the face of it, two new papers published this week about the genetics of type 2 diabetes (T2D) seem somewhat contradictory. The first, an enormous genome-wide association study (GWAS) published in the journal Nature Genetics, has thrown up a plethora of new loci associated with fasting glucose level [Dupuis J, et al. Nature Genetics (2010) doi:10.1038/ng.520], which is itself a useful clinical predictor of the development of T2D. The Meta-Analysis of Glucose and Insulin-related traits Consortium (MAGIC) conducted meta-analyses of 21 GWAS, and followed up 25 loci in a second replication phase in order to validate 16 new loci associated with fasting glucose levels in over 120,000 non-diabetic participants. These included eight loci that have also been shown to increase the risk of developing T2D in a separate case-control studies. These loci point to numerous likely candidate genes involved in insulin production, glucose sensing and pancreatic beta-cell proliferation and development.

    New Gene ID'd in Brittle Bone Disease
    BusinessWeek , 20-Jan-2010

    ABSTRACT: A new gene involved in a recessive form of brittle bone disease has been pinpointed by researchers.

    Identification of the Gene Responsible for a New Form of Adult Muscular Dystrophy
    ScienceDaily , 22-Jan-2010

    ABSTRACT: A study published in the January 21 online edition the American Journal of Human Genetics, allowed the first identification of a new form of adult onset muscular dystrophy. The research team led by Dr. Bernard Brais, neurogeneticist at the Research Centre of the Centre hospitalier de l'Université de Montréal (CRCHUM) and associate professor, Université de Montréal, in collaboration with European collaborators, demonstrated that recessive ANO5 mutations will lead to abnormal membrane repair of muscle fibers.

    Study Suggests Non-Genetic Factors are Better Type 2 Diabetes Risk Predictors than Genetics
    genomeweb , 20-Jan-2010

    ABSTRACT: Based on findings from the Whitehall II prospective study, a team of University College London researchers concluded that two non-genetic risk models more accurately predicted type 2 diabetes risk than a genetic model based on 20 risk alleles.

    S. Florida scientists work to decode the genetics of chocolate
    The Miami Herald , 21-Jan-2010

    ABSTRACT: No one who loves chocolate needs to be told that it is experiencing a golden age. The very fact that the names of illustrious cacao types like Venezuelan Porcelana have made their way onto chocolate-bar labels shows a deepening hunger for vivid cacao character and careful artisanship.

    Study says genetics unlikely to be behind increased rates of H1N1 in aboriginals
    Canadian Press , 16-Jan-2010

    ABSTRACT: TORONTO — A new study says genetic susceptibility is unlikely to be responsible for increased rates of severe H1N1 cases in aboriginal people.

    Gene discovery may help guide breast cancer care
    Reuters , 24-Jan-2010

    ABSTRACT: CHICAGO (Reuters) - An abnormality in two genes can make a common class of chemotherapy drugs used to fight breast cancer less effective, U.S. researchers said on Sunday in a finding that could help doctors better tailor treatments.

    Minor Genetic Disorders Resulting In Embryos Being Destroyed
    TopNews , 25-Jan-2010

    ABSTRACT: Pre-implantation genetic diagnosis is gaining popularity amongst potential parents to avoid passing on inherited genetic conditions to their children. However, this is resulting in the destruction of embryos with minor genetic disorders such as thalassaemia and the Marfan syndrome.

    New Genetic Links for Pancreatic Cancer
    WebMD Health News , 25-Jan-2010

    ABSTRACT: Jan. 25, 2010 -- At least three newly discovered genetic variants may contribute to pancreatic cancer risk, according to a new study. Researchers say it’s the largest study to date to identify potential genetic risk factors for the mysterious disease.

    A New Way to Look for Diseases’ Genetic Roots
    The New York Times , 25-Jan-2010

    ABSTRACT: The hunt for the genetic roots of common diseases has hit a blank wall.

    The genetic variants found so far account in most cases for a small fraction of the genetic risk of the major killers. So where is the missing heritability and why has it not showed up?

    Childhood cancer gene search to start
    CBC News , 27-Jan-2010

    ABSTRACT: Researchers plan to map all the genes in childhood tumours to identify mutations that give rise to the cancers.

    St. Jude Children's Research Hospital in Memphis, Tenn., and Washington University school of medicine in St. Louis, Mo., announced the project on Monday. A similar international project aims to sequence all the genes in 20 common cancers in adults.

    Gene Therapy Study Seeks to Improve Brain Function in Alzheimer's Disease
    ScienceDaily , 26-Jan-2010

    ABSTRACT: Alzheimer's disease (AD) researchers are testing the effectiveness of gene therapy for the first time to treat patients with this common brain disease. Emory University is one of 12 institutions participating in a nationwide study to test the experimental medication, CERE-110.

    Genetic Risk Factor Identified for Parkinson's Disease
    Science Daily (press release) , 17-Jan-2010

    ABSTRACT: An international team of doctors and human geneticists has identified a new genetic risk factor for Parkinson's disease. The institutions involved in the study were the Institute of Human Genetics of Helmholtz Zentrum München and Technische Universität München, the Neurological Clinic of Ludwig-Maximilians-Universität Munich (LMU) and the Mitochondrial Research Group of Newcastle University, Newcastle upon Tyne, UK.

    Genetic Variant Linked to Deadly Prostate Cancer
    FOOD CONSUMER , 17-Jan-2010

    ABSTRACT: Sunday Jan 17, 2010 (foodconsumer.org) -- For the first time, researchers at Wake Forest University Baptist Medical Center have identified a genetic variant associated with aggressive prostate cancer, according to a new study.

    Britain: New wave of human BSE/vCJD feared
    World Socialist Web Site , 27-Dec-2008

    ABSTRACT: Prion protein production in the bodies of humans and animals is controlled by a particular gene. To date those humans that have died from vCJD have had a particular genetic makeup. Such gene types are classed as MM, comprising up to 42 percent of the population, with 47 percent of the population having so-called MV genes and the remaining 11 percent having what is called a VV genetic makeup.

    The current news reports concern a young man diagnosed as having vCJD but with genes of the MV type. If the diagnosis of vCJD is confirmed (this can only be done by invasive procedures such as brain biopsy) his will be the first case to occur outside the MM genetic group.

    Gene linked to prostate cancer found
    Press TV , 12-Jan-2010

    ABSTRACT: A genetic mutation linked to the development of an aggressive form of prostate cancer in men has been recently discovered.

    According to the study published in the Proceedings of the National Academy of Sciences, men with a certain gene variant known as single nucleotide polymorphisms (SNPs) are 26 percent more likely to develop aggressive prostate cancer — the second-leading cancer killer.

    Green tea 'may block lung cancer'
    BBC News , 13-Jan-2010

    ABSTRACT: Among smokers, those who did not drink green tea at all were more than 12 times as likely to develop lung cancer than those who drank at least a cup a day.

    Researchers then analysed the DNA of people in the study and found certain genes appeared to play a role in the risk reduction.

    Green tea drinkers, whether smokers or non smokers, with certain types of a gene called IGF1, were far less likely to develop lung cancer than other green tea drinkers with different types of this gene.

    Gene linked to prostate
    Press TV , 12-Jan-2010

    ABSTRACT: A genetic mutation linked to the development of an aggressive form of prostate cancer in men has been recently discovered.

    According to the study published in the Proceedings of the National Academy of Sciences, men with a certain gene variant known as single nucleotide polymorphisms (SNPs) are 26 percent more likely to develop aggressive prostate cancer — the second-leading cancer killer.

    Technique to screen embryos 'increases risks in multiple pregnancies'
    Telegraph.co.uk , 22-Dec-2009

    ABSTRACT: Screening embryos for genetic illnesses can increase fivefold the chance of death in the days before and after birth, research has indicated.

    Blacks Have Less 'Bad Fat' Than Whites
    AJC , 18-Dec-2009

    ABSTRACT: Blacks tend to carry around less of a particularly unhealthy type of abdominal fat than whites, even though they suffer more from obesity-linked illness, researchers report

    'Full genetics of cancer mapped'
    NURSING times.net , 21-Dec-2009

    ABSTRACT: Many newspapers have reported that scientists have “cracked the code” of cancer with the analysis ofthe entire genetic sequence of malignant melanoma skin cancer and an aggressive form of lung cancer.

    DNA Sequencing Used to Attack Lung Cancer
    Science Daily (press release) , 16-Dec-2009

    ABSTRACT: ScienceDaily (Dec. 17, 2009) — Aided by next-generation DNA sequencing technology, an international team of researchers has gained insights into how more than 60 carcinogens associated with cigarette smoke bind to and chemically modify human DNA, ...

    Gene code of common cancers mapped
    World News Australia , 18-Dec-2009

    ABSTRACT: Two common forms of cancer have been genetically mapped for the first time, British scientists say, in a major breakthrough in understanding the diseases. The maps have exposed the DNA mutations that lead to skin and lung cancers, in a discovery ...

    15 cigarettes all it takes to harm genes - study
    New Zealand Herald , 16-Dec-2009

    ABSTRACT: Photo / AP One genetic mutation occurs on average for every 15 cigarettes that a typical lung-cancer patient smokes, according to a study that has identified for the first time all of the mutations acquired during the lifetime of a ...

    15 Cigarettes Equal One DNA Mutation
    Medical News Today , 18-Dec-2009

    ABSTRACT: "15 cigarettes equal one DNA mutation" captures graphically the enormity of what was discovered when a UK-led team of scientists reported this week how they cracked the code of two killer cancers: small cell lung cancer and malingnant melanoma. ...

    Scientists unlock genetic code in major cancer breakthrough
    CNN  , 17-Dec-2009

    ABSTRACT: London, England (CNN) -- The entire genetic codes of two common types of cancer have been cracked, according to scientists, who say the breakthrough could unlock a new era in the treatment of deadly diseases. Scientists at the UK-based ...

    The bespoke cancer 'cure': British scientists decode the DNA of lung and skin ...
    Daily Mail  , 16-Dec-2009

    ABSTRACT: The breakthrough could lead to 'bespoke' treatments tailored for individual patients, as well as better detection. In the landmark study, Cambridge University researchers charted the thousands of pieces of damage to DNA which turn ...

    Scientists Crack Genetic Code of Two Common Cancers
    Voice of America  , 18-Dec-2009

    ABSTRACT: It is being called a scientific breakthrough. British researchers say they have mapped the entire genetic code for two types of cancers -- small cell lung cancer and melanoma, the most deadly type of skin cancer. All cancers are caused by changes in ...

    Professor Mike Stratton: "This is a fundamental moment in cancer research"
    BBC News  , 16-Dec-2009

    ABSTRACT: Scientists have unlocked the entire genetic code of two of the most common cancers - skin and lung - a move they say could revolutionise cancer care. Not only will the cancer maps pave the way for blood tests to spot tumours far ...

    First cancer genome sequences reveal how mutations lead to disease
    guardian.co.uk  , 16-Dec-2009

    ABSTRACT: The number of mutations in the cells of a lung cancer patient suggest one permanent mutation is caused for every 15 cigarettes smoked. Photograph: AFP/Getty Images Scientists have reconstructed the biological history of two types of cancer in a genetic ...

    Genetic map of tumours reveals thousands of mutations
    Times Online , 17-Dec-2009

    ABSTRACT: Moderate smokers can expect to inflict a new mutation on their DNA every day, the first catalogue of the genetic changes found in lung cancer has suggested. The genetic map of a 55-year-old man's tumour has revealed 22910 different mutations, ...

    British scientists crack killer cancer code
    Telegraph.co.uk , 17-Dec-2009

    ABSTRACT: The genetic code of two of the most deadly cancers has been cracked by British scientists in a world first that opens up a whole new era in the treatment for the disease. By Richard Alleyne, Science Correspondent All the mutations that turn healthy …

    The Big Question: Has a key breakthrough been made in the search for a cure for cancer?
    Independent , 18-Dec-2009

    ABSTRACT: Why are we asking this now? British scientists announced yesterday that they have sequenced a "cancer genome" for the first time. It means they have identified all of the many thousands of genetic mistakes that make a tumour cell different from a healthy cell taken from the same cancer patient.

    Smoking just 15 cigarettes harms your DNA, finds cancer study on gene mutation
    Daily Mail , 17-Dec-2009

    ABSTRACT: Smokers experience one mutation to their DNA for every 15 cigarettes they smoker, according to a study that mapped out the genetic blueprint of a lung cancer patient.

    Cancer treatment takes a giant step forward as scientists crack code
    The Times , 17-Dec-2009

    ABSTRACT: The complete genetic codes of two human cancers have been mapped for the first time. The move could herald a medical revolution in which every tumour can be targeted with personalised therapy

    Genetic breakthrough hails new cancer research era
    Telegraph.co.uk , 16-Dec-2009

    ABSTRACT: The genetic code of two of the most deadly cancers has been cracked by British scientists in a world first that opens up a whole new era in the treatment for the disease

    Gene maps to transform scientists' work on cancer
    Yahoo news , 16-Dec-2009

    ABSTRACT: Scientists have identified all the changes in cells of two deadly cancers to produce the first entire cancer gene maps and say the findings mark a "transforming moment" in their understanding of the disease. Skip related content

    We're winning the war on cancer
    Telegraph.co.uk , 18-Dec-2009

    ABSTRACT: Extraordinary scientific advances mean we can now look forward to an era when cancer is no longer a condition to be feared, says Karol Sikora, one of the world's leading experts in the disease.

    Obesity gene discovery 'may cut cases blamed on abuse'
    BBC News , 06-Dec-2009

    ABSTRACT: Scientists have discovered what they believe is a genetic cause of severe obesity in children.

    Genetic anomaly promotes childhood obesity
    China View , 07-Dec-2009

    ABSTRACT: BEIJING, Nov. 7 (Xinhuanet) -- Some children get severely obese because they lack particular genes, which kicks their hunger into overdrive, according to Sunday's journal Nature.

    Men's genes 'may limit lifespan'
    BBC News , 02-Dec-2009

    ABSTRACT: Men carry the seeds of their own destruction in the genes present in their sperm, research suggests.

    Kangaroo DNA system could help prevent skin cancer
    China View , 30-Nov-2009

    ABSTRACT: CANBERRA, Nov. 30 (Xinhua) -- Australian researchers revealed on Monday that finding out how kangaroos repair their DNA could be the key to preventing skin cancer.

    Genes found to be main cause of graying hair
    Press TV , 01-Dec-2009

    ABSTRACT: While many consider environmental factors such as stress, diet and smoking as the main factors leading to graying hair, a new study finds genes to be more important.

    Gene protecting body against bowel cancer found
    Press TV , 25-Nov-2009

    ABSTRACT: Gene protecting body against bowel cancer found US researchers have discovered that a gene, formerly known to protect the body against harmful chemicals, can shield an individual against bowel cancer.

    Genetic clue to glioma brain cancer growth
    WPN(World Press Network ) , 23-Nov-2009

    ABSTRACT: Scientists have pinpointed a mutated gene as key to the development of some types of glioma brain tumour.

    The New England Journal of Medicine (NEJM)
    The New England Journalof Madicine

    ABSTRACT: The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice. Material is published with an emphasis on internal medicine and specialty areas including allergy/immunology, cardiology, endocrinology, gastroenterology, hematology, kidney disease, oncology, pulmonary disease, rheumatology, HIV, and infectious diseases.

    NEJM Online contains both the current issue and an online archive that can be accessed through browsing, advanced searching, or collections by disease or topic.

    ScienceDaily
    science daily

    ABSTRACT: ScienceDaily is one of the Internet’s most popular science news web sites. Since starting in 1995, the award-winning site has earned the loyalty of students, researchers, healthcare professionals, government agencies, educators and the general public around the world. Now with more than 3 million monthly visitors, ScienceDaily generates nearly 15 million page views a month and is steadily growing in its global audience.

    NextBio
    NextBio

    ABSTRACT: NextBio is the provider of an innovative platform that enables life science researchers to search, discover, and share knowledge locked within public and proprietary data. NextBio's platform seamlessly combines powerful tools with unique correlated content to transform information into knowledge, providing the foundation for new scientific discoveries.

    ALFRED (The ALlele FREquency Database)
    ALFRED (The ALlele FREquency Database)

    ABSTRACT: A resource of gene frequency data on human populations supported by the U. S. National Science Foundation.

    TheLancet.com
    lancent.com

    ABSTRACT: The Lancet's prestigious heritage as one of the world's leading medical journals continues to inspire our authors and editors today as they strive for medical excellence in all that they publish…

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