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  • Related Articles

    Listed below are links to news, reports, and discussion articles related to the science of DNA gene screening.

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    Study shows gene diversity among neighboring Africans
    THE ASSOCIATED PRESS , 21-Feb-2010

    ABSTRACT: Scientists who decoded the DNA of some southern Africans have found striking new evidence of the genetic diversity on that continent - and uncovered a surprise about the ancestry of Archbishop Desmond Tutu.

    Common Gene Variant May Increase Risk for a Type of Cardiac Arrhythmia
    ScienceDaily , 22-Feb-2010

    ABSTRACT: An international research team has identified a common gene variant associated with a form of the irregular heartbeat called atrial fibrillation. In their report in the journal Nature Genetics, being published online, the investigators describe finding that variations affecting a protein that may help control the heart's electrical activity appear to increase the risk of what is called lone atrial fibrillation (AF), a type seen in younger individuals with no other form of heart disease.

    Study examines link between genetics and cancer
    Student life , 10-Feb-2010

    ABSTRACT: Washington University has undertaken an unprecedented study of cancer tumors with the help of St. Jude’s Children’s Hospital in an effort to pinpoint genetic mutations that play a role in causing cancer.

    Single Gene Mutation Induces Endometrial Cancer
    ScienceDaily , 12-Feb-2010

    ABSTRACT: A mutation in a single gene can cause endometrial cancer that is responsive to a specific drug therapy, researchers at UT Southwestern Medical Center have found in an animal study.

    Bowel cancer gene hotspots find will tailor treatment
    BBC News  , 10-Feb-2010

    ABSTRACT: Scientists have found genetic hotspots for bowel cancer they say will help doctors better treat the disease.

    Irritable Bowel Syndrome Blog
    About.com , 08-Feb-2010

    ABSTRACT: You may have read the story back in the year 2000 about a town in Ontario in which over two thousand residents became ill due to tainted water. Apparently a longitudinal study found that more than a third of those infected developed post-infectious IBS (IBS-PI). More recently, a study has been published that looked to see if genetics had anything to do with why some residents developed ongoing problems with IBS and others did not.

    Researchers Identify Genetic Variant Linked to Faster Biological Aging
    Scientific American , 08-Feb-2010

    ABSTRACT: Individuals carrying the variant had shorter telomeres, stretches of DNA at the ends of chromosomes that protect them from daily wear--and also aging

    Scientists Find Gene Variant Link to Aging Cells
    Reuters , 09-Feb-2010

    ABSTRACT: Scientists have found specific genetic variants which may explain why some people age earlier than others and say their findings have important implications for understanding cancer and age-related diseases.

    Method of the Future Uses Single-Cell Imaging to Identify Gene Interactions
    ScienceDaily , 09-Feb-2010

    ABSTRACT: Cellular imaging offers a wealth of data about how cells respond to stimuli, but harnessing this technique to study biological systems is a daunting challenge. In a study published online in Genome Research, researchers have developed a novel method of interpreting data from single-cell images to identify genetic interactions within biological networks, offering a glimpse into the future of high-throughput cell imaging analysis.

    Gene That Improves Quality of Reprogrammed Stem Cells Identified
    ScienceDaily , 08-Feb-2010

    ABSTRACT: n the 7 Feb. 2010 issue of the journal Nature, scientists at the Genome Institute of Singapore (GIS), report that a genetic molecule, called Tbx3, which is crucial for many aspects of early developmental processes in mammals, significantly improves the quality of stem cells that have been reprogrammed from differentiated cells.

    Gene variants in mother and infant increase risk of pre-term labor
    Top News , 07-Feb-2010

    ABSTRACT: Researchers at the National Institutes of Health (NIH) have recently reported that the gene variants in the mother and the fetus play a notable role in the risk of pre-term labor – one of the main causes of infant disability and mortality.

    Gene Variants Linked To Risk Of Preterm Birth
    Medical News Today , 08-Feb-2010

    ABSTRACT: Gene variants in a woman and her fetus can make them more susceptible to an inflammatory response to infections inside the uterus, which can increase the risk for a preterm birth, according to a study presented at a meeting of the Society for Maternal-Fetal Medicine

    Premature birth gene clue found
    BBC News  , 05-Feb-2010

    ABSTRACT: DNA differences which appear to affect the risk of giving birth early have been found by US scientists.

    Women With Variants in “CLOCK” Gene Have Higher Risk of Breast Cancer
    insciences , 03-Feb-2010

    ABSTRACT: A Yale University-led team of researchers has demonstrated for the first time that variants in a gene responsible for regulating the body’s circadian rhythm may lead to breast cancer. The study appears as an OnlineFirst publication of the journal Cancer Research.

    DNA Methylation Could Change Gene Expression
    Bio IT World.com , 03-Feb-2010

    ABSTRACT: Researchers at the Genome Institute of Singapore and The Scripps Research Institute have shown dramatic changes in DNA methylation as stem cells differentiate and the patterns revealed could influence transcription and gene expression. The results were published on Wednesday in Genome Research.

    Prostate cancer cells spreads with gene function loss
    The Times of India , 03-Feb-2010

    ABSTRACT: A new research has shown that prostate cancer cells are more likely to spread to other parts of the body if a specific gene quits functioning normally

    Loss of Gene Function Makes Prostate Cancer Cells More Aggressive
    Science News , 02-Feb-2010

    ABSTRACT: Prostate cancer cells are more likely to spread to other parts of the body if a specific gene quits functioning normally, according to new data from researchers at UT Southwestern Medical Center.

    Rights group argues against human gene patent
    Reuters , 02-Feb-2010

    ABSTRACT: Patents on two human genes associated with breast and ovarian cancer should be declared invalid because they stifle the free flow of information and hamper research, lawyers told a New York judge on Tuesday.

    Austrian scientists curb obesity in mice by modifying ‘hedgehog’ gene
    Top News , 08-Jan-2010

    ABSTRACT: Scientists from Austrian Academy of Sciences, Institute for Molecular Biotechnology (IMBA) and Institute of Molecular Pathology at Austria's University of Salzburg have discovered that gene therapy can play a notable role in slowing down the formation of unwanted fat in the body, by suppressing the growth of white fat cells.

    Biologists Develop Efficient Genetic Modification of Human Embryonic Stem Cells
    ScienceDaily , 08-Jan-2010

    ABSTRACT: Biologists have developed an efficient way to genetically modify human embryonic stem cells. Their approach, which uses bacterial artificial chromosomes to swap in defective copies of genes, will make possible the rapid development of stem cell lines that can both serve as models for human genetic diseases and as testbeds on which to screen potential treatments,

    Periodic Paralysis Study Reveals Gene Causing Disorder
    ScienceDaily , 09-Jan-2010

    ABSTRACT: Scientists have identified a gene underlying a disease that causes temporary paralysis of skeletal muscle. The finding, they say, illustrates how investigations of rare genetic diseases can drive insights into more common ones.

    Finding breast cancer genes
    The Star Online , 10-Jan-2010

    ABSTRACT: With more knowledge about genetics, scientists are now beginning to make a stronger link between a woman’s genetic make-up and breast cancer risk.

    Gene Reverses Diabetes?
    Ivanhoe Newswire , 11-Jan-2010

    ABSTRACT: Even a very small amount of the fat hormone leptin goes a long way when it comes to correcting diabetes. The hormone controls the activity of a gene in the liver, which has anti-diabetic effects in animals and could have similar therapeutic effect in humans.

    Scientists find new leukemia gene risk factors
    Reuters , 10-Jan-2010

    ABSTRACT: Researchers have found four new genetic variants that increase the risk of contracting one of the major forms of leukemia, confirming that risk factors for the fatal blood cancer can be inherited.

    Research on cocaine reveals gene-altering roots of addiction
    Reuters , 08-Jan-2010

    ABSTRACT: Prolonged exposure to cocaine can cause permanent changes in the way genes are switched on and off in the brain, a finding that may lead to more effective treatments for many kinds of addiction

    Scientists find gene that regulates your heart beat
    Telegraph.co.uk , 11-Jan-2010

    ABSTRACT: Experts hope that the discovery of the "pacemaker gene" could lead to new drug treatments to avoid heart attacks and disease.

    deCODE Finds Genetic Factors Impacting Key Clinical Measurements of Heart Activity and Disease Risk
    PRNewswire , 10-Jan-2010

    ABSTRACT: Novel SNPs Modulate ECG Measurements Including Heart Rate, Two are Also Risk Factors for Atrial Fibrillation and Will be Integrated Into deCODE AF(TM) Test

    Rheumatologists Advance Genetic Research Related to Disabling Form of Arthritis
    ScienceDaily , 11-Jan-2010

    ABSTRACT: Work done in part by researchers at The University of Texas Health Science Center at Houston has led to the discovery of two new genes that are implicated in ankylosing spondylitis (AS), an inflammatory and potentially disabling disease. In addition, the international research team pinpointed two areas along stretches of DNA that play an important role in regulating gene activity associated with the arthritic condition.

    Embryo genetic screening controversial - and successful
    USA TODAY , 10-Jan-2010

    ABSTRACT: A "slippery slope" to "a world of eugenics," as bioethics authorities once worried, or a healthy life for a teenage girl?

    Study indicates dogs make excellent models for studying human genetic disorders
    THE MEDICAL NEWS , 31-Jan-2010

    ABSTRACT: In the new Swedish-Finnish study, published in Nature Genetics, the researchers identified five loci that predispose to an SLE-related disease in Nova Scotia duck tolling retrievers. The study indicates that the homogeneity of strong genetic risk factors within dog breeds make dogs an excellent model in which to identify pathways involved in human complex diseases. The results of the study also open the door for further studies of specific T-cell activation pathways in human populations.

    Breast Cancer Campaign: Gene Could Predict Tamoxifen Treatment Failure
    BUSINESS WIRE , 01-Feb-2010

    ABSTRACT: Scientists in Belfast have identified a gene which could predict whether women with breast cancer will respond to treatment with tamoxifen, according to findings published today in Cancer Research.

    Gene "dictates cancer drug effects"
    Pharmacy Europe , 02-Feb-2010

    ABSTRACT: High levels of a specific gene in breast cancer tumours may provide the tell-tale signs of whether the patient will respond to a commonly used drug therapy or not, university scientists have found.

    Dog studies may help understand human genetic disorders
    Daily News & Analysis ]DNA , 02-Feb-2010

    ABSTRACT: A new Swedish-Finnish study has indicated that dogs can provide an excellent model for understanding human complex diseases.

    Gene that controls heart beat discovered
    UPI , 11-Jan-2010

    ABSTRACT: Discovery of a gene that regulates heart beat could lead to new treatments for cardiac rhythm disturbances, British researchers said.

    Genetic Factors Can Increase Leukaemia Risk Seven-Fold
    HealthCanal.com , 11-Jan-2010

    ABSTRACT: Scientists have found four new regions of the genome that increase the risk of a common blood cancer, according to results published today in the journal Nature Genetics.

    Genetic breast cancer test soon available at mammography
    ABC 4 News , 14-Jan-2010

    ABSTRACT: “This is an extraordinary advancement if you think about it. That from a blood test, we can tell someone if they have a particular high risk of disease, and we can give them strategies that will help them lower that risk.” Dr. Gregory Critchfield , MD, MS and President of Myriad Genetics Laboratory is proud of the work done to discover the gene mutation BRCA1 AND BRCA2, and the work to create a test that could save the lives of millions of women at hereditary risk of developing breast, and ovarian cancer. The challenge has been getting the word out.

    Gene Mutation Tied to Increased Risk of Aggressive Prostate Cancer
    dbtechno.com , 12-Jan-2010

    ABSTRACT: Boston (DbTechNo) - A new gene mutation has been discovered that may explain why some men are especially prone to developing prostate cancer.

    Skip the Chemotherapy? Gene Tests Help Breast Cancer Patients Make That Decision
    U.S.News , 12-Jan-2010

    ABSTRACT: Ask any woman with breast cancer if she'll do all that it takes to prevent a recurrence, and chances are she'll say, "Of course!" Yet she probably wouldn't choose to have chemotherapy—and the hair loss, nausea, fatigue, and potentially serious medical complications that come with it—if told that it probably wouldn't do much to lower an already low risk of relapse. Turns out, a genetic test called Oncotype DX that predicts a woman's chances of recurrence is, indeed, affecting doctors' and patients' decisions when it comes to chemotherapy, according to a study published Monday in the Journal of Clinical Oncology. About one third of the time, oncologists in the study changed their treatment recommendations after seeing the test result and about one quarter of the patients chose not to have unnecessary chemotherapy.

    Could a genetic cholesterol control protect some people from dementia?
    Scientific American , 12-Jan-2010

    ABSTRACT: The more information about cholesterol's complex health role that comes to light, the more curious are the ways it seems to be important.

    Scientists Decode Brain Cancer Cell Line
    HealthDay News , 29-Jan-2010

    ABSTRACT: The first complete genomic sequencing of a brain cancer cell line has been performed by U.S. scientists.

    Genetics and Alzheimer's: To know or not to know?
    TBO.com , 30-Jan-2010

    ABSTRACT: Last year, a study in the New England Journal of Medicine asked whether the children of Alzheimer's patients should find out whether they were genetically predisposed to the same fate. Researchers concluded that people who learned their genetic status could take the information in stride as long as they received appropriate counseling.

    Genetic contribution to human behaviour
    guardian.co.uk , 28-Jan-2010

    ABSTRACT: In his latest rant against genetics, Oliver James either does not understand, or ­wilfully misunderstands, the genetic basis of neurobiology, and purposefully overlooks huge swathes of scientific literature (Nature v nurture – what are the latest genetic ­findings, 23 January).

    Genetic testing for breast cancer: Ancestry makes a difference
    MayoClinic.com , 27-Jan-2010

    ABSTRACT: Genetic testing for hereditary breast and ovarian cancer syndrome, due to mutations in the BRCA1 and BRCA2 genes, has become a relatively routine practice. If you meet with a genetic specialist to discuss testing, they will likely ask about your ancestry as part of the evaluation.

    Gene map for malaria crop offers higher yield hope
    Reuters , 14-Jan-2010

    ABSTRACT: Genetic map designed to help scientists improve crop yield Increased malaria funding will push up artemisinin demand Experts aim to get high-yield seed to farmers in 2-3 years The first genetic map of a medicinal herb used in the best malaria treatments is being published to help scientists develop the species into a high-yielding crop and battle the killer mosquito-borne disease.

    Scientists identify gene that creates skin wrinkles in Shar-peis
    DAILY NEWS , 15-Jan-2010

    ABSTRACT: Scientists have found the gene that genetically predisposes these cuddly pooches to grow extra-wrinkly rolls of skin, BBC News reports.

    Genetic Risk Factor Identified for Parkinson's Disease
    ScienceDaily , 17-Jan-2010

    ABSTRACT: An international team of doctors and human geneticists has identified a new genetic risk factor for Parkinson's disease. The institutions involved in the study were the Institute of Human Genetics of Helmholtz Zentrum München and Technische Universität München, the Neurological Clinic of Ludwig-Maximilians-Universität Munich (LMU) and the Mitochondrial Research Group of Newcastle University, Newcastle upon Tyne, UK.

    Women at high cancer risk need genetic counseling, care
    hometownlife.com , 17-Jan-2010

    ABSTRACT: A genetic mutation can significantly increase a woman's risk of developing breast cancer and ovarian cancer. But does that mean everyone should be tested?

    Newly Identified Gene Variants Linked to Diabetes
    HealthDay News , 18-Jan-2010

    ABSTRACT: Researchers have identified 10 new gene variants associated with blood sugar or insulin levels, which they believe could lead to new treatments for type 2 diabetes.

    New genetic markers discovered for diabetes traits
    Cordis News , 18-Jan-2010

    ABSTRACT: The work of an international team of scientists has helped unravel the biological blueprint of type 2 diabetes (T2D). Funded in part by the EU, the two major parallel studies were conducted by researchers representing more than 100 institutes and using genetic data from over 100,000 individuals. The discovery of common genetic variants associated with T2D risk and blood glucose levels is published in two corresponding reports in Nature Genetics.

    New Study Links Gene Variants to Diabetes Development
    Better Health Research , 19-Jan-2010

    ABSTRACT: Although natural diabetes remedies may help keep symptoms at bay, scientists have discovered five new gene variants that could raise blood sugar, increasing the risk of developing type-2 diabetes.

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