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  • Related Articles

    Listed below are links to news, reports, and discussion articles related to the science of DNA gene screening.

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    SNP Database Now Available to Genomics Researchers
    Biotech Daily , 18-Aug-2010

    ABSTRACT: Advanced genomics researchers now have access to collections comprising up to 7.4 million single-nucleotide polymorphisms (SNPs) that can be used to assemble microarrays containing from 50,000 to 2.6 million SNPs.

    Genetic screening, preventive surgery raise cancer survival rates--study
    The Money Times , 01-Sep-2010

    ABSTRACT: Women carrying BRCA1 or BRCA2, the common cancer gene mutations, can cut their risk of death, breast cancer and ovarian cancer by opting for pre-emptive removal of breasts or ovaries, findings of a new study suggest.

    First Genetic Link Found for Common Migraine
    WebMD Health News , 30-Aug-2010

    ABSTRACT: Researchers a Step Closer to Unlocking Mysteries of Migraines

    Genetic Links to Autism
    The Future of Things , 24-Jul-2010

    ABSTRACT: Researchers at Oxford University in England have found a non-hereditary genetic link to autism. They have shown that individuals with autism tend to have either missing or extra sectors of DNA segments, a genetic mistake called copy number variants. This discovery could lead to easier identification and diagnosis of the disease as well as a potential avenue for new treatments or even a cure for the disease.

    Exercise cuts genetic obesity risk by 40 percent: study
    The age.com.au , 01-Sep-2010

    ABSTRACT: Physical exercise can reduce a genetic predisposition to obesity by an average of 40 percent, a new study showed.

    Revolutionary new scan shows key to migraines is in the genes
    The Independent , 30-Aug-2010

    ABSTRACT: A revolutionary way of screening the entire human genome for the genetic signposts of disease has produced its latest success – the first inherited link to common migraine and a possible reason for extreme headaches.

    Kids swap DNA for fairground rides
    Nature News , 01-Sep-2010

    ABSTRACT: Researchers' efforts to collect samples at a fair raise ethical questions.

    Unlocking The Genetic Secrets Of Autism
    Forbes , 28-Jul-2010

    ABSTRACT: A new study will spread greater awareness of the public health benefits of wider immunization.

    Genetic changes linked to diet, alcohol could predict breast cancer severity
    Sify , 31-Jul-2010

    ABSTRACT: Epigenetic changes to DNA in breast cancers are directly linked with diet, alcohol, and tumour size, and could hence give a glimpse of the severity of the disease, according to researchers from Brown University and the University of California San Francisco.

    Genetic Link Between Two Rare Diseases Established By Next Generation Sequencing
    Medical News Today (press release) , 31-Jul-2010

    ABSTRACT: Scientists have successfully used "next generation sequencing" to identify mutations that may cause a rare and mysterious genetic disorder. The research, published by Cell Press on July 29th in the American Journal of Human Genetics, demonstrates that sequencing an affected individual's entire "exome"; that is, all of the genes that carry instructions for producing proteins, can reveal critical genes that when mutant, cause inherited disorders.

    Genetic research highlights vitamin D disease role
    NutraIngredients-usa.com , 24-Aug-2010

    ABSTRACT: Vitamin D has a significant effect on at least 229 genes some of which have been associated with Crohn’s disease and type 1 diabetes, according to UK and Canadian researchers.

    VA Works Genetics and Colorectal Cancer
    Veterans Today Network , 27-Aug-2010

    ABSTRACT: HAVE YOU HEARD?

    The ability to determine a patient’s increased genetic risk of disease and provide appropriate health care is emerging as a component of personalized medicine in VA and is now available to VA clinicians for the first time in history.

    Scientists link genetic 'typos' to schizophrenia
    Globe and Mail , 27-Aug-2010

    ABSTRACT: An ambitious multi-million dollar Canadian project to identify hundreds of genes essential to communication between brain cells has led to the discovery that random mutations not inherited from either parent play a role in schizophrenia.

    Expanding genetic testing center helps high-risk patients plan their treatment.
    Lancaster Newspapers , 29-Aug-2010

    ABSTRACT: After learning her mother tested positive for a genetic mutation that can lead to cancer, Kristin Gilhool decided to get tested, too.

    First genetic link found to common migraine
    msnbc.com , 29-Aug-2010

    ABSTRACT: An international scientific team has identified for the first time a genetic risk factor associated with common migraines and say their research could open the way for new treatments to prevent migraine attacks.

    95 genetic variants linked to heart disease found
    The Times of India , 05-Aug-2010

    ABSTRACT: An international team of researchers co-led by the University of Michigan School of Public Health has found 95 regions of the human genome where genetic variants are associated with blood cholesterol and triglyceride levels, which are major indicators of heart disease risk.

    Read more: 95 genetic variants linked to heart disease found - Health - Health & Fitness - Life & Style - The Times of India http://timesofindia.indiatimes.com/life-style/health-fitness/health/95-genetic-variants-linked-to-heart-disease-found/articleshow/6260126.cms#ixzz0yAqiwJgT

    Scientists identify genetic basis for prostate cancer susceptibility in non-European population
    News-Medical.net , 02-Aug-2010

    ABSTRACT: A genome-wide study on Japanese subjects has identified 5 new genetic variations associated with prostate cancer and revealed differences and similarities between Europeans and Asians in susceptibility to the disease. Reported in Nature Genetics, the findings offer a first-ever glimpse of the genetic basis for prostate cancer susceptibility in a non-European population.

    Genetic Risk Score Associated With Breast Cancer Risk; Predictive Of Type Of Disease
    Medical News Today , 02-Aug-2010

    ABSTRACT: Women with higher risk scores that consisted of having certain genetic variants most strongly linked to breast cancer had an associated higher risk of breast cancer, with these scores also highly predictive of estrogen receptor-positive disease, according to a study in the July 28 issue of JAMA.

    Cloned animals a 'threat to genetic diversity'
    The Ecologist , 04-Aug-2010

    ABSTRACT: Report highlights the danger of cloning to animal health as campaigners also warn it will reduce genetic diversity within herds

    New guidelines for direct-to-consumer genetic tests
    Cancer Research UK , 04-Aug-2010

    ABSTRACT: A set of guidelines has been published to protect people using DIY genetic tests for inherited diseases, such as certain types of breast cancer.

    DIY genetics tests' guidelines published
    BBC News Health , 04-Aug-2010

    ABSTRACT: Experts concerned about the availability of DIY genetic tests have launched guidelines for the industry.

    Gene that causes Parkinson's disease identified
    Telegraph.co.uk , 28-Jul-2010

    ABSTRACT: Parkinson's disease sufferers have been offered new hope after the gene mutation which triggers it was identified by scientists.

    Study: Presence of Murine Leukemia Virus Related Gene Sequences Found in CFS Patients
    PR Newswire (press release) , 23-Aug-2010

    ABSTRACT: Researchers have found murine leukemia viruses (MLV) related gene sequences in blood samples collected from patients diagnosed with chronic fatigue syndrome (CFS) and some healthy blood donors, according to a study published online today by the scientific journal Proceedings of the National Academy of Sciences (PNAS).

    BVH offers test on genetic probability of breast cancer
    13abc.com , 23-Aug-2010

    ABSTRACT: Blanchard Valley Hospital's Woman Wise mammography department has partnered with Myriad Genetics to offer a test to determine risk for hereditary breast and ovarian cancer. This new test is called the BRACAnalysisBlanchard Valley Hospital's Woman Wise mammography department has partnered with Myriad Genetics to offer a test to determine risk for hereditary breast and ovarian cancer. This new test is called the BRACAnalysis.

    Genetic link between Parkinson’s disease and immune system
    WebMD Health News , 17-Aug-2010

    ABSTRACT: New evidence that Parkinson’s disease may have an infectious or autoimmune origin has been discovered by a team of US researchers

    Genetic variant that substantially increases schizophrenia risk identified
    Sify , 06-Aug-2010

    ABSTRACT: Scientists have discovered a genetic variant that substantially increases the risk for developing schizophrenia.

    The genetics of blood cholesterol
    NHS Choices , 05-Aug-2010

    ABSTRACT: Genes, not diet, may increase your chances of getting heart disease

    Researchers find 'strong evidence' of genetic link to contracting meningitis
    The Guardian , 09-Aug-2010

    ABSTRACT: Discovery that gene mutations can determine whether a person develops meningitis could help in the search for a vaccine

    Genetic Variants Confer Susceptibility to Meningococcal Disease
    TopNews United States , 10-Aug-2010

    ABSTRACT: A genome wide association study in addition to two replication studies were conducted by the scientists at the Genome Institute of Singapore a biomedical research institute of the Agency for Science, Technology and Research along with the colleagues from the UK, Austria, Spain and The Netrgerlands. Major genetic variants that confer susceptibility to Meningococcal disease were discovered with the help of the study.

    Dogs' physical traits controlled by small number of genetic regions
    PhysOrg.com , 10-Aug-2010

    ABSTRACT: Sure, dogs are special. You might not be aware, however, that studying their genomes can lead to advances in human health. So next time you gaze soulfully into a dog's eyes or scratch behind its ears, take note of the length of his nose or the size of his body. Although such attributes can vary wildly among different breeds, a team of investigators co-led by researchers at Stanford University School of Medicine, Cornell University and the National Human Genome Research Institute has found that they are determined by only a few genetic regions.

    Genetic cause of gall bladder stones found
    Business Standard , 13-Aug-2010

    ABSTRACT: Hyderabad-based Asian Institute of Gastroenterology (AIG) has come out with a new finding that there is a specific genetic defect that causes gallstone disease (GSD)among Indian patients.

    Diabetes health centre
    WebMD Health News , 28-Jun-2010

    ABSTRACT: UK researchers in international study find 12 new genes linked to type 2 diabetes

    Gene linked to autoimmune diseases
    Nature News , 16-Jun-2010

    ABSTRACT: Rare variants of a single gene seem to make patients more susceptible to multiple diseases

    A wake-up call for dozing Drosophila
    Nature News , 14-Jun-2010

    ABSTRACT: Association study shows that the genetics of sleep are as complex in flies as in humans.

    New blood fat heart disease link
    BBC News , 06-May-2010

    ABSTRACT: A type of blood fat different from cholesterol may play a key role in heart disease, a study suggests.

    Girl frozen in time may hold key to ageing
    Times Online , 09-May-2010

    ABSTRACT: American scientists are keenly studying the DNA of a 17-year-old girl who still has the body and behaviour of a baby

    Parent's view on genetic link to autism: 'I don't want it to be eradicated'
    The Guardian, , 10-Jun-2010

    ABSTRACT: Charlotte Moore, who has two sons with autism, reflects on newly discovered genetic links to autism

    Refining the Prostate Cancer Genetic Association within the JAZF1 gene on chromosome 7p15.2
    URO TODAY , 03-May-2010

    ABSTRACT: Background: Genome-wide association studies have identified multiple genetic variants associated with susceptibility to prostate cancer (PrCa). In the two-stage Cancer Genetic Markers of Susceptibility prostate cancer scan, a single-nucleotide polymorphism (SNP), rs10486567, located within intron 2 of JAZF1 gene on chromosome 7p15.2, showed a promising association with PrCa overall (P = 2.14 x 10(-6)), with a suggestion of stronger association with aggressive disease (P = 1.2 x 10(-7)). Methods: In the third stage of genome-wide association studies, we genotyped 106 JAZF1 SNPs in 10,286 PrCa cases and 9,135 controls of European ancestry. Results: The strongest association was observed with the initial marker rs10486567, which now achieves genome-wide significance [P = 7.79 x 10(-11); OR(HET), 1.19 (95% confidence interval, 1.12-1.27); OR(HOM), 1.37 (95% confidence interval, 1.20-1.56)]. We did not confirm a previous suggestion of a stronger association of rs10486567 with aggressive disease (P = 1.60 x 10(-4) for aggressive cancer, n = 4,597; P = 3.25 x 10(-8) for nonaggressive cancer, n = 4,514). Based on a multilocus model with adjustment for rs10486567, no additional independent signals were observed at chromosome 7p15.2. There was no association between PrCa risk and SNPs in JAZF1 previously associated with height (rs849140; P = 0.587), body stature (rs849141, tagged by rs849136; P = 0.171), and risk of type 2 diabetes and systemic lupus erythematosus (rs864745, tagged by rs849142; P = 0.657). Conclusion: rs10486567 remains the most significant marker for PrCa risk within JAZF1 in individuals of European ancestry. Impact: Future studies should identify all variants in high linkage disequilibrium with rs10486567 and evaluate their functional significance for PrCa. Cancer Epidemiol Biomarkers Prev; 19(5);

    Two new gene mutations linked to autism
    WebMD Health News , 03-May-2010

    ABSTRACT: Researchers have discovered two new genes that may be involved with autism, the brain disorder marked by difficulty in communicating and relating to others.

    Gene may be key to response to ADHD drug
    UPI.com , 04-May-2010

    ABSTRACT: researchers say gene research may help those taking drugs for attention-deficit hyperactivity disorder.

    Exercise can help fight 'obesity' gene
    One India , 05-May-2010

    ABSTRACT: Physically active lifestyle during adolescence can reduce the effect of a mutation in a gene that predisposes someone to becoming overweight or obese, says a study led by Spanish researchers.

    Sources of genetic resistance to rice sheath blight identified
    DNA India , 05-May-2010

    ABSTRACT: Sources of genetic resistance to sheath blight, a major disease affecting rice production worldwide, have been identified by Agricultural Research Service (ARS) scientists.

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